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It also reduces apoptosis of immune cells through improved cellular signaling, and it helps balance the Th1/Th2 ratio, a parameter that is frequently skewed in autoimmune conditions

Transaminases, bilirubin, alkaline phosphatase, albumin, and markers of synthetic function point toward a hepatic cause when they are abnormal

Cmpl = complementary treatments (containing acetyl-l-carnitine)

Hereby, a few drugs and factors that have proved useful in protecting OLGs and white matter as a whole using different models are discussed, a summary of which can be seen in Table 1

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