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In addition, TN medicines may lose effectiveness with time

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Flavonoids are important because they act as free-radical scavengers and antioxidants, exhibiting anti-mutagenic, anti-inflammatory, and antiviral effects[and] are able to reduce plasma levels of low-density lipoproteins, inhibit platelet aggregation, and reduce cell proliferation. (Salehi, 2019)

It causes sharp, stabbing pain along the trigeminal nerve, which carries sensations from the face to the brain

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