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Western diets high in sugar, fat, and n-6 PUFA disrupt the gut barrier by increasing pro-inflammatory mediators, whereas Mediterranean diets rich in dietary fiber, plant polyphenols, and n-3 PUFA enhance microbiota diversity and promote the production of anti-inflammatory metabolites, such as SCFAs, thereby alleviating intestinal inflammation [247,248,249]

2005;supp B:S15-S21

Lots of drugs or strategies have been developed and applied on clinical trial ( Table 3 ), such as DMARDs, biologic agents, TCM, cell transfer, gene therapy, vaccine and nano drug delivery system, to treat RA with both advantages and shortcomings

21JC1406000), and CAMS Innovation Fund for Medical Sciences (Grant No

Glutathione yang dikonsumsi secara oral dapat meningkatkan kadar sistein, sulfat plasma, dan glutathione darah utuh

Other organs damaged by alcohol and the effects of omega-3 DHA alleviates testosterone fall due to early ethanol exposure and recovers the low steroidogenic acute regulatory protein mRNA caused by PNEE in adolescence, responsible for cholesterol transport into mitochondria needed for testosterone synthesis