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Molecular mechanisms of glutamate toxicity in Parkinsons disease

Multi-omics integration revealed a high-inflammation, high-oxidation, low-metabolism triad, which is mainly regulated by the Stat1-(2-carboxypropyl)-Cysteamine-C3 interaction axis

Commonly known as carcinogens, or mutagens in technical terms, they include free radicals, reactive oxygen species (ROS), certain chemicals and radiation

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Indeed, these synthetic routes can be performed under mild conditions, insensitive to oxygen and water, proceed in benign solvents, show stereospecificity and generate inoffensive byproducts that can be removed without the use of chromatographic methods (Hein et al., 2008