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nucleus accumbens, etc.), which is implicated in euphoria and repeated substance use [9,10,11]

Pai-Nong-San (PNS) demonstrated significant therapeutic effects in ameliorating AOM/DSS-induced colonic injury in mice, as evidenced by the alleviation of hematochezia, reduction of disease activity index (DAI) scores, increase in colon length, and reversal of pathological alterations