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Furthermore, Gclc -deficient FoB have a block in the mitochondrial electron transport chain (ETC) due to diminished complex I and II activity and thereby accumulate the tricarboxylic acid cycle metabolite succinate

Nemkov, T., Yoshida, T., Nikulina, M

Here, well skip the basics and focus on the involvement of the gut and gut microbiota

Mediators Inflammation (2020) 2020:1693730

This relationship persists on multivariate logistic regression controlling for age, ethnicity, MELD, and etiology of cirrhosis (data not shown)

These findings demonstrate that melittin and BV exert their anti-inflammatory effects through a dual mechanism, targeting both NF-B and JNK pathways