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Phosphorylation of OPTN by TANK-binding kinase 1 (TBK1) enhances its capacity to bind to poly-Ub chains, thus creating a positive feedback cycle that promotes mitophagy [66, 67]

It slows down how the kidneys remove amoxicillin from the body, causing higher levels of amoxicillin to stay in your system longer

found that SFN significantly lowers Toll-like receptor 4 (TLR4) and interferon regulatory factor 1 (IRF1) levels in a CaOx kidney stone model by activating Nrf2

10.3892/ijmm.2023.5317 47 ZhuJ.XuK.ZhangX.CaoJ.JiaZ.YangR.et al (2016)