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Nuclear factor E2-related factor 2 (Nrf2), a key transcription factor and endogenous antioxidant, maintains cellular metabolic homeostasis, redox state, and protein homeostasis

Specifically, oxygen consumption enables to meet increased energy demands in neural circuits by facilitating oxidative phosphorylation in the mitochondria and thus, contributing to the generation of adenosine triphosphate (ATP) 14,55,56

Starting with a lower dose and gradually increasing it allows users to gauge their bodys reaction and minimize side effects

Additionally, their larger size and chemical properties make it difficult for them to be absorbed through the intestinal wall into the bloodstream

doi: 10.1021/acsnano.4c00227 190 WangXLiMRenKXiaCLiJYuQet al

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