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Immune checkpoint inhibitors: Review and management of endocrine adverse events

ALCAR functionally inhibits angiogenesis in vitro We have previously shown that ALCAR inhibits endothelial cells by regulating angiogenesis in hypoxic and inflammatory conditions in vitro and in vivo [30]

10.1016/j.neuint.2018.08.007 4 BaralP.UditS.ChiuI

Iron overload increases the severity of inflammatory processes, in which there is not only a consistent relationship between seizures and inflammatory cytokines (IL-6, TNF-, and IFN, etc.) but also the inflammation itself generates increased iron deposits [7]

doi:10.21037/tlcr.2016.06.07 9

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