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Protective effect of saponins of panax notoginseng on drug-induced liver injury in mice

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In the late stages of pregnancy, slower glycine de novo synthesis limits the ability of adolescent mothers to maintain glycine flux and compromises fetal growth 22

The Wnt receptor Ryk reduces neuronal and cell survival capacity by repressing FOXO activity during the early phases of mutant huntingtin pathogenicity

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This can be achieved either with a solution of a competing ligand or by changing the buffer conditions of the mobile phase, for example to high or low pH, elevated salt concentration, or by applying a chemical denaturant, detergent or chelating agent