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doi: 10.1200/JCO.2022.40.16_suppl.TPS2678 323 GroteSUrea-BailnGChanKC-HBadenCMezgerMHandgretingerRet al

Materials and methods Study population Sixty PCR-confirmed SARS-CoV-2 infected individuals comprised of 30 LC patients, 15 individuals without LC symptoms who were previously infected with SARS-CoV-2 but recovered without any symptoms per se (recovered group, denoted R), 15 acute hospitalized COVID-19 patients) as well as 15 healthy controls (HCs) without acute symptoms and negative SARS-CoV-2 immunoassays ( Figure 1A , Supplementary Table 1 )

A groundbreaking study has unveiled that lactylation of the Lys131 residue at the N-terminus of cGAS by AARS2 in the wake of viral infection leads to a loss of DNA recognition capacity

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Targher G, Mantovani A, Byrne CD