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mansoni juvenile worms, the LD 50 of PZQ (413 M) is inferior to that of inhibitors 1 - 5 (7.2 60% reduction in worm burden, a significantly higher efficacy than observed for treatment with PZQ in previous studies 13 , which had 0% reduction at 21 and 28 d.p.i

One case-control study reported that selenium-responsive glutathione peroxidase 1 (GPx1) activity was significantly lower in Keshan patients compared to healthy individuals

Additionally, overcoming key obstacles such as the BBB and drug efflux is crucial for improving drug delivery and minimizing tumor recurrence

Studies with mouse models have shown that hepsin is important for maintaining hepatic structural homeostasis, liver metabolism, and adipocyte browning (Hsu et al

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