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Tobacco dependence often manifests as a chronic, relapsing condition, with the majority of smokers crossing prolonged periods of tobacco use combined with several attempts to quit

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A growing body of research suggests that the dysregulation of the nicotinic cholinergic system is responsible for modulating the sensory processing input processes, which accounts for the control issues that are typical of ADHD [73] nAChRs also have a role in the regulation of neurotransmitters including dopamine and serotonin