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This powerful, naturally occurring compound is known for promoting youthful skin, supporting liver detoxification, and fighting free radical damage

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The modulation of the vasomotor system involves ROS as mediators of vasoconstriction induced by angiotensin II, endothelin-1 and urotensin-II, among others

Increased intestinal permeability, chronic inflammation, oxidative stress, -synuclein aggregation, and neurotransmitter imbalances are some key factors that govern gastrointestinal pathology and PD progression

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There is still a gap in existing research in the field, necessitating well-designed, robust, multicenter clinical trials with sensitive endpoints and standardized protocols to facilitate the diagnosis of DPN via a simple and effective algorithm and to track the progression of disease and treatment response