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Not entirely

High-dose oral cyanocobalamin (1,000 mcg daily) is effective for many patients after sleeve gastrectomy, as a small proportion is absorbed passively without intrinsic factor

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It's a formidable, often-unseen barrier to progress

The data is earlier-stage and most of the human work comes from outside the U.S

The doses range from 2 to 6 IU each day