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Albuterol is longer acting than isoproterenol in most patients by any route of administration because it is not a substrate for the cellular uptake processes for catecholamines or for COMT Less than 20% of a single albuterol dose is absorbed systemically following nebulizer administration Albuterol does not readily cross the blood brain barrier Bronchodilation is maximal in ~15 minutes, and persists for 3-4 hours

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Ameer B, Weintraub RA, Johnson JV, Yost RA, Rouseff RL (1996) Flavanone absorption after naringin, hesperidin, and citrus administration

Discovery of bacteroides uniformis F18-22 as a safe and novel probiotic bacterium for the treatment of ulcerative colitis from the healthy human colon