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It is to note that reference [19] provides further details on this calculation method

On the one hand, DCs within the TME frequently display an immature or tolerogenic phenotype, characterized by reduced expression of costimulatory molecules and impaired cross-presentation capacitylimitations that hinder their ability to prime nave T cells, as discussed earlier [123, 124]

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Stragierowicz, J

Electron microscopy sample preparation and imaging were performed with devices supported by the Microscopy Imaging Center (MIC) of the University of Bern, Switzerland