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This review discusses the critical role of redox biology in human health, exploring the essential equilibrium between oxidative stress and antioxidant mechanisms for cellular function and overall vitality

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(1) Neurodevelopmental Homeostasis: In the healthy state, mitochondrial oxidative phosphorylation (Complexes IV) supports efficient ATP generation, redox stability, and formate flux from the mitochondrial folate cycle (via SHMT2, MTHFD2)

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