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[DOI] [PMC free article] [PubMed] [Google Scholar] 137.Vinchi F., Sparla R., Passos S.T., Sharma R., Vance S.Z., Zreid H.S., Juaidi H., Manwani D., Yazdanbakhsh K., Nandi V., et al

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However, the subsequent reperfusion, meant to restore normal blood flow, exacerbates the damage through the formation of reactive oxygen species (ROS), inflammatory mediators, and the activation of numerous signaling pathways (Snchez-Hernndez et al., 2020)

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The criteria for protein identification included (1) a calculated false discovery rate 39 below 1%, (2) all the proteins must have been identified with more than two unique peptides and (3) all peptide signals (heavy/light isotope labelling) for each protein must have at least a fourfold enrichment in FUS/TLS immunoprecipitates compared with the LAP control (purified from the parental HeLa cell line)

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