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Pseudomonas aeruginosa pyocyanin activates NRF2-ARE-mediated transcriptional response via the ROS-EGFR-PI3K-AKT/MEK-ERK MAP kinase signaling in pulmonary epithelial cells

Additionally, molecules such as nicotinamide, statins, and neurotrophic factors are being explored for their potential benefits (Figure 3)

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The metatarsal bones were cultured for 6 days with replacement of medium every 3 days

This is where glucose-centric treatment becomes essential to protect -cells and is ripe for pharmaceutical intervention

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