As more of the nicotine is absorbed by the body in high-dose exposure, symptoms transition to lethargy, depression, low blood pressure, normal or elevated heart rate, paralysis, respiratory depression or arrest, and death
In both genders, the geometric cadmium concentration was significantly different according to smoking status
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[10] In most cases, the illness will resolve on its own within one to two days, but symptoms may be so severe as to require emergency medical treatment which could include medication to treat nausea and vomiting and IV fluids
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