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2022]Review Diabetes-Associated Mutations in Proinsulin Provide a "Molecular Rheostat" of Nascent Foldability

GFAT, glutamine fructose-6-phosphate aminotransferase

Specifically, Ganoderma lucidum polysaccharides have been reported to inhibit liver fibrosis (27)

These properties derive from the fact that any charged particle that is spinning generates a magnetic field

Consequences: Doubles apparent molecular weight on SEC May induce artificial dimerization of the passenger protein Can mask or distort protein-protein interactions For crystallization: GST dimer may dominate crystal contacts For some applications, the forced dimerization is actually useful (e.g., studying avidity effects)

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