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The soft-tissue evidence for both compounds is overwhelmingly rodent and cell-culture

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Increased antitumor activity of bevacizumab in combination with hypoxia inducible factor-1 inhibition

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Since MTHFR deficiency is one of the treatable metabolic disorders not identified by current newborn mass screening, we should consider the possibility of MTHFR deficiency in adolescents with mental retardation who display abnormally elevated homocysteine in association with progressive neurological or psychiatric dysfunction and leukoencephalopathy