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To also evaluate the sample processing quality of streamlined workflow, we compared it to our previous stateoftheart protocol for the processing of deparaffinized FFPE tissue in a 96well format (Coscia et al , 2020) by processing a subset of liver tissues from our cohort both on the same LC and MS instruments

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Results: Analysis of data from the GEO database revealed that PATZ1 expression was significantly decreased in liver cirrhosis patients, negatively correlated with fibrosis severity