giving b12 injections to cats for Kittens — Kitten Lady Vitamin B12 Deficiency in Cats:

It increases intestinal motility, pancreatic secretion, and biliary secretion (this may be one of the reasons Cheney believes he sees reduced biliary secretion ejection fractions in the gall bladder in almost every patient), stomach pepsin secretion, it inhibits stomach acid, and it increases chronotropism and inotropism in the heart (Rx chronic heart failure?) Its a potent pulmonary vasodilator

Complications are rare, particularly if the injections are performed using a precise needle-positioning technique

What is the molecular structure of 5-Amino-1MQ

Vitamins E and C, beta-carotene, and other carotenoids

Rather than taking a high dose of one single one on its own, it's better to take a good combination

NAD+ BENEFITS Selective NNMT inhibition substrate-site targeting with minimal off-target activity in preclinical models NAD+ salvage modulation studied for increasing intracellular NAD+ and SAM availability Adipose metabolism investigated for suppression of adipocyte lipogenesis in 3T3-L1 models Small molecule distinct mechanism from peptide-based metabolic compounds (GLP-1 agonists, etc.) Defined pharmacology IC of 1.2 M confirmed in published enzymatic assays WHAT RESEARCHERS LOOK AT NNMT enzyme inhibition kinetics and SAM/1-MNA substrate balance NAD+ and SAM level changes in adipocyte and hepatocyte cell models Lipogenesis suppression in 3T3-L1 differentiated adipocyte assays Polyamine flux enzyme upregulation (ODC, SSAT) and histone methylation In vivo efficacy in diet-induced obesity (DIO) murine models