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It plays a fundamental role in maintaining cellular health, primarily by serving as a potent antioxidant and participating in various enzymatic reactions throughout the body

The imbalance between the availability of lipids in the liver and their metabolism (e.g., catabolism and transport) contributes to hepatic steatosis, a reversible condition that occurs in both ALD and MASLD that can progress to advanced stages, such as alcoholic steatohepatitis and MASH that ultimately can culminate in HCC [114116]

6.4.3 Structural silencing and interaction mapping Advancements in drug-target interaction mapping, facilitated by AI-driven docking and high-resolution cryo-electron microscopy, enable the intentional silencing of binding sites

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