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Shortness of breath can also occur due to the reduced oxygen-carrying capacity of the blood

Side effects include water retention, increased hunger, and occasionally numbness or tingling in extremities

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While much of the research remains in preclinical stages, early findings are promising

Unlike oral medications that compete for stomach absorption, intramuscular or sublingual B12 bypasses the digestive system entirely, making it an ideal pairing for GLP-1 users

311,312,313 It has recently been demonstrated that MIF inhibits the GC-induced leucine zipper (GILZ) expression via a unique set of effects on transcription factor expression and phosphorylation, and regulation by MIF of MKP-1 and MAPK activation are mediated through GILZ (Fig